鲜天南星水提取物对小鼠子宫纤维瘤的抑制作用和对小鼠雌激素的影响

【摘要】目的 探讨鲜天南星水提取物对小鼠子宫纤维瘤的抑制作用及对小鼠雌激素水平的影响。方法 选取SD健康雌性小鼠30只，随机分为正常组、模型组、实验组3组，每组各10只，对模型组、实验组进行子宫纤维瘤模型建立，正常组不作处理。实验组小鼠予以鲜天南星水提取物进行干预，正常组、模型组小鼠注射等体积生理盐水。对小鼠子宫重及子宫系数进行统计计算，酶联免疫吸附试验法检测雌二醇（Estradiol，E2）、孕酮（Progesterone，P）、卵泡刺激素（Follicle stimulating hormone，FSH）、黄体生成激素（Luteinizing Hormone，LH）水平。结果 干预后，模型组及实验组小鼠子宫重及子宫系数均高于正常组，实验组小鼠子宫重及子宫系数均低于模型组（P＜0.05）；干预后，模型组及实验组小鼠血清E2、P、FSH、LH水平均高于正常组，但实验组小鼠血清E2、P、FSH、LH水平均低于模型组（P＜0.05）。结论 鲜天南星水提取物可对小鼠子宫纤维瘤起到一定的抑制作用，并能对E2、P、FSH、LH等激素水平进行调控，为子宫纤维瘤的临床治疗提供一定的理论依据，值得临床借鉴。     

温病学教学中的“三全育人”战略

温病学是中医学四大经典课程之一,是基础理论向临床实践过渡的桥梁课程,对于中医药高校学生具有重要意义。“三全育人”战略是高校思想政治工作的重点,新时期,我们应把“三全育人”战略贯穿温病学教育教学全过程和各环节,全员全过程全方位为培养具有坚实的温病理论知识和技能、医德高尚的现代化应用型中医药人才服务。     

中西医不同角度对儿童新型冠状病毒肺炎(COVID-19)的认识

2019年12月以来,以湖北省武汉市为中心陆续发现了多例新型冠状病毒肺炎(COVID-19)患者。人群普遍易感,儿童亦有感染病例出现,感染波及新生儿、婴幼儿,并且已出现儿童重症病例。儿童感染病例引起了社会高度重视。目前COVID-19病理机制尚不清楚,治疗亦缺乏特效药,这些问题都给疫情防控和临床救治带来极大困难。尝试从中西医不同角度认识儿童COVID-19,分析儿童COVID-19病因、流行特点、病情发展特点及治疗措施,同时从中医角度探讨儿童COVID-19病因病机、辨证及治疗方法,能更好地通过中西医结合对此次儿童COVID-19进行深入了解,理解其病理之基础,分析目前疫情发展之趋势,并在此基础上寻找安全有效的防治措施,以期对临床更好地防治儿童COVID-19提供参考。     

Infections at the bottom end of the gastrointestinal tract

This article concentrates on specific infections of the distal gastrointestinal (GI) tract, particularly those that are transmitted sexually, by anal intercourse. Syphilis, gonorrhoea and lymphogranuloma venereum (LGV) are age old and well known diseases, but the features may be unfamiliar to GI histopathologists. Every histopathology trainee will have seen Herpes simplex virus (HSV) infection of squamous epithelium (e.g. oesophagus, vulva and anus), but the HSV pseudotumour of the anus/perineum can present a pitfall to those who have not previously encountered this entity. Another, more recently described, entity that has a predilection for the ano-rectal region is Epstein–Barr Virus (EBV) positive mucocutaneous ulcer, and this also presents a diagnostic trap to the unwary.     

Caliber-persistent labial artery: report of 3 cases

The caliber-persistent labial artery is a vascular anomaly in which a primary arterial branch penetrates into the submucosal tissue without reduction in diameter. Most lesions are benign and do not require treatment, except for complications and/or on patient demands. In this way, noninvasive diagnostic tools are preferred such as high-resolution and color Doppler ultrasonography which allow direct observation of the lesion, assessing its exact location and diameter at every axis, as well as the blood flow velocity. An excisional biopsy of these lesions or even their surgical extirpation could have a fatal outcome with profuse bleeding.